Drug Standards
Medchemexpress LLC Gemcitabine monophosphate | 116371-67-6 | 99.98% | 343.18 | 10 MG
Gemcitabine monophosphate is an active intermediate of Gemcitabine, designed for research use. It exhibits a synergistic anti-cancer effect and can be delivered by formulating it into nanoparticles. It has been shown to induce tumor cell apoptosis and reduce tumor cell proliferation.
- Has a synergistic anti-cancer effect
- Can be delivered by formulating it into nanoparticles
- Induces tumor cell apoptosis (30-40%)
- Reduces tumor cell proliferation (by 8 times)
- Significantly reduces tumor microvessel density (MVD)
- Inhibits tumor mitosis
TARGETMOL CHEMICALS INC DINOPROST TROMETHAMINE S 25MG
Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Dinoprost tromethamine salt (PGF2(alpha) THAM) is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient. purity: 99%
Medchemexpress LLC Naphazoline | 835-31-4 | 99.7% | 210.27 | 100 MG
Naphazoline (Naphthazoline) is a potent α-adrenergic receptor agonist that reduces vascular hyperpermeability and promotes vasoconstriction. It can also reduce levels of inflammatory factors, cytokines, IgE, GMCSF, and NGF, making it suitable for non-bacterial conjunctivitis research.
- Reduces vascular hyperpermeability
- Promotes vasoconstriction
- Reduces levels of inflammatory factors (TNF-α, IL-1β and IL-6)
- Reduces levels of cytokines (IFN-γ and IL-4)
- Reduces levels of IgE, GMCSF, and NGF
- Can be used for non-bacterial conjunctivitis research
Medchemexpress LLC Itacitinib adipate | 1334302-63-4 | 99.2% | 699.66 | 5 MG
Itacitinib adipate is an orally bioavailable and selective JAK1 inhibitor that has been tested for efficacy and safety in a phase II trial in myelofibrosis. It is suitable for research use only.
- Orally bioavailable
- Selective JAK1 inhibitor
- Tested in phase II trial for myelofibrosis
- Suitable for research use
Medchemexpress LLC Folic acid-13C5 | 1207282-75-4 | 95.0% | 446.36 | 500 UG
Folic acid-13C5 is the 13C-labeled Folic acid. Folic acid (Vitamin M; Vitamin B9) is a B vitamin; it is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis. This product is for research use only and not sold to patients.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Ranitidine | 66357-35-5 | MFCD00081180 | 99.9% | 25 MG
Ranitidine is a potent, selective, and orally active histamine H2-receptor antagonist that inhibits gastric secretion. It has been shown to inhibit breast tumor development and spread in mice, and also antagonizes histamine-induced effects in isolated rat tissues.
- Potent, selective, and orally active H2-receptor antagonist
- Inhibits gastric acid secretion
- Antagonizes histamine-induced effects in isolated rat atrium and uterine horn
- Inhibits breast tumor development and spread
- Reduces specific myeloid cell populations in mice
- Increases latency of breast tumorigenesis
Medchemexpress LLC Ketorolac (tromethamine salt) | 74103-07-4 | MFCD00887595 | 99.5% | 1 G
Ketorolac tromethamine salt is a non-steroidal anti-inflammatory agent that acts as a nonselective COX inhibitor. With IC50s of 20 nM for COX-1 and 120 nM for COX-2, this compound is intended for laboratory chemical use and substance manufacturing, and is for research use only.
- Non-steroidal anti-inflammatory agent
- Nonselective COX inhibitor
- Solid appearance
- Purity of 99.5%
- IC50 of 20 nM for COX-1
- IC50 of 120 nM for COX-2
Medchemexpress LLC Amodiaquine impurity 1 | 81099-86-7 | 270.72 | 500 MG
Amodiaquine impurity 1 is a chemical identified as an impurity of Amodiaquine. It is intended for research use only by experienced personnel in laboratory settings for the manufacture of substances. This product has not been fully validated for medical applications.
- Store at 4°C, protected from light, and under nitrogen.
- In solvent, store at -80°C for up to 6 months or -20°C for up to 1 month, protected from light and under nitrogen.
- Soluble in DMSO at 20 mg/mL (73.88 mM) with ultrasonic, warming, and heating to 60°C.
Medchemexpress LLC Detomidine hydrochloride | 90038-01-0 | 99.8% | 5 G
Detomidine hydrochloride is an imidazole derivative and a potent α2-adrenergic agonist. It provides dose-dependent analgesic effects through the activation of α2 catecholamine receptors, leading to reduced production of excitatory neurotransmitters. This product also has cardiac, respiratory, and antidiuretic actions due to its inhibition of the sympathetic nervous system. It is currently licensed for use in horses.
- Potent α2-adrenergic agonist
- Provides dose-dependent analgesic effects
- Activates α2 catecholamine receptors
- Inhibits the sympathetic nervous system
- Exhibits cardiac, respiratory, and antidiuretic actions
- Licensed for use in horses
Medchemexpress LLC Colchicine | 64-86-8 | 99.93% | 399.44 | 25 MG
Colchicine (Standard) is the analytical standard for Colchicine, an orally active alkaloid. It acts as a potent tubulin inhibitor and a microtubule disrupting agent, inhibiting microtubule polymerization with an IC50 of 3 nM. It also functions as a competitive antagonist of α3 glycine receptors (GlyRs) and can prevent NSAID-induced small intestinal injury. Colchicine demonstrates extensive anti-inflammatory, immunosuppressive, and anti-fibrosis effects, suggesting its potential for gouty arthritis research.
- Analytical standard for research and analytical applications.
- Potent tubulin inhibitor and microtubule disrupting agent.
- Inhibits microtubule polymerization with an IC50 of 3 nM.
- Competitive antagonist of the α3 glycine receptors (GlyRs).
- Prevents NSAID-induced small intestinal injury.
- Extensive anti-inflammatory, immunosuppressive, and anti-fibrosis effects.
- Potential for gouty arthritis research.
Medchemexpress LLC Lenalidomide-C5-acid | 2338824-30-7 | 96.36% | 373.40 | 100 MG
Lenalidomide-C5-acid is a Lenalidomide-based E3 ligase ligand-linker conjugate that recruits CRBN protein and can be used to synthesize PROTACs. It is designed for high-speed applications and has a range of documented technical specifications.
- Recruits CRBN protein
- Can be used to synthesize PROTACs
- Available in various sizes
Medchemexpress LLC Lenalidomide 4'-PEG1-amine dihydrochloride | 2624336-86-1 | 98.37% | 419.30 | 5 MG
Lenalidomide 4'-PEG1-amine dihydrochloride is a Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. It can be connected to the ligand for protein by a linker to form PROTAC.
- Lenalidomide-based Cereblon ligand
- Used in the recruitment of CRBN protein
- Can be connected to the ligand for protein by a linker to form PROTAC
- For research use only
Medchemexpress LLC Naftifine hydrochloride | 65473-14-5 | 99.7% | 250 MG
Naftifine hydrochloride is an antibiotic with antifungal activity against dermatophytes, aspergilli, Sporothrix schenckii, and yeasts of the genus Candida. It can be used for the research of superficial dermatomycoses inhibition.
- Antifungal activity against dermatophytes, aspergilli, and yeasts
- Used for superficial dermatomycoses inhibition research
Medchemexpress LLC Methylprednisolone | 83-43-2 | 99.8% | 1 G
Methylprednisolone is a synthetic corticosteroid with anti-inflammatory and immunomodulating properties. It improves severe or critical COVID-19 by activating ACE2 and reducing IL-6 levels. This compound is commonly used for anti-inflammatory purposes and can be utilized in the study of bronchial inflammation or acute bronchitis caused by arthritis and various respiratory diseases. It can also improve neurological recovery in acute spinal cord injury.
- Synthetic corticosteroid
- Anti-inflammatory and immunomodulating properties
- Improves severe or critical COVID-19 by activating ACE2 and reducing IL-6 levels
- Commonly used for anti-inflammatory purposes
- Can be used in the study of bronchial inflammation or acute bronchitis
- Can improve neurological recovery in acute spinal cord injury
- Targets glucocorticoid receptor
- Molecular formula: C22H30O5
- Molecular weight: 374.47
Medchemexpress LLC Nitisinone | 104206-65-7 | 100 MG
Nitisinone is an orally active, competitive, and reversible 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) inhibitor with an IC50 of 173 nM. It promotes tyrosine accumulation in a dose-dependent manner and can be used in studies of hereditary tyrosinemia type 1 (HT-1) and albinism.
- Orally active and competitive 4-HPPD inhibitor
- Promotes tyrosine accumulation
- Useful in studies of hereditary tyrosinemia type 1 (HT-1)
- Applicable in studies of albinism